Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer
The insulin-like growth factor (IGF) system exerts pleiotropic effects on mammalian cells. This review focuses on type I IGF receptor (IGF1R)-mediated signal transduction and its relevance in breast cancer. Upon activation by the IGFs, IGF1R, a transmembrane tyrosine kinase receptor, undergoes autop...
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| Pubblicato in: | Breast Cancer Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr50 |
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