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A Functional IL-13 Receptor is Expressed on Polarized Murine CD4+ Th17 Cells and IL-13 Signaling Attenuates Th17 Cytokine Production()

IL-17A is produced from Th17 cells, and is involved in many autoimmune and inflammatory diseases. The IL-13 receptor (IL-13R) has not previously been reported to be functionally expressed on T cells; however, we found that purified BALB/c CD4+ cells polarized to Th17 with TGF-β, IL-6, and IL-23 have...

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Detalhes bibliográficos
Main Authors: Newcomb, Dawn C., Zhou, Weisong, Moore, Martin L., Goleniewska, Kasia, Hershey, Gurjit K. K., Kolls, Jay K., Peebles, R. Stokes
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711250/
https://ncbi.nlm.nih.gov/pubmed/19380778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803868
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