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Surface for Catalysis by Poliovirus RNA-Dependent RNA Polymerase

The poliovirus RNA-dependent RNA polymerase, 3Dpol, replicates the viral genomic RNA on the surface of virus-induced intracellular membranes. Macromolecular assemblies of 3Dpol form linear array of subunits that propagate along a strong protein-protein interaction called interface-I, as was observed...

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Main Authors: Wang, Jing, Lyle, John M., Bullitt, Esther
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711085/
https://ncbi.nlm.nih.gov/pubmed/23583774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.007
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