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Structure of the C-terminal region of an ERG channel and functional implications
The human ether-à-go-go–related gene (hERG) encodes a K(+) channel crucial for repolarization of the cardiac action potential. EAG-related gene (ERG) channels contain a C-terminal cyclic nucleotide-binding homology domain coupled to the pore of the channel by a C-linker. Here, we report the structur...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710865/ https://ncbi.nlm.nih.gov/pubmed/23801759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306887110 |
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