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On the mechanism of recombination hotspot scanning during double-stranded DNA break resection

Double-stranded DNA break repair by homologous recombination is initiated by resection of free DNA ends to produce a 3′-ssDNA overhang. In bacteria, this reaction is catalyzed by helicase–nuclease complexes such as AddAB in a manner regulated by specific recombination hotspot sequences called Crosso...

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Hlavní autoři: Carrasco, Carolina, Gilhooly, Neville S., Dillingham, Mark S., Moreno-Herrero, Fernando
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710824/
https://ncbi.nlm.nih.gov/pubmed/23798400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303035110
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