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Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase–nuclease

In all domains of life, the resection of double-stranded DNA breaks to form long 3′-ssDNA overhangs in preparation for recombinational repair is catalyzed by the coordinated activities of DNA helicases and nucleases. In bacterial cells, this resection reaction is modulated by the recombination hotsp...

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Autors principals: Gilhooly, Neville S., Dillingham, Mark S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027173/
https://ncbi.nlm.nih.gov/pubmed/24682829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku188
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