Dual Nuclease and Helicase Activities of Helicobacter pylori AddAB Are Required for DNA Repair, Recombination, and Mouse Infectivity

Helicobacter pylori infection of the human stomach is associated with disease-causing inflammation that elicits DNA damage in both bacterial and host cells. Bacteria must repair their DNA to persist. The H. pylori AddAB helicase-exonuclease is required for DNA repair and efficient stomach colonizati...

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Bibliographic Details
Main Authors: Amundsen, Susan K., Fero, Jutta, Salama, Nina R., Smith, Gerald R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719311/
https://ncbi.nlm.nih.gov/pubmed/19395381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005587
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