High-Throughput Automated Phenotyping of Two Genetic Mouse Models of Huntington's Disease

Phenotyping with traditional behavioral assays constitutes a major bottleneck in the primary screening, characterization, and validation of genetic mouse models of disease, leading to downstream delays in drug discovery efforts. We present a novel and comprehensive one-stop approach to phenotyping,...

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Bibliographic Details
Main Authors: Balci, Fuat, Oakeshott, Stephen, Shamy, Jul Lea, El-Khodor, Bassem F., Filippov, Igor, Mushlin, Richard, Port, Russell, Connor, David, Paintdakhi, Ahmad, Menalled, Liliana, Ramboz, Sylvie, Howland, David, Kwak, Seung, Brunner, Dani
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
HD Models
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710674/
https://ncbi.nlm.nih.gov/pubmed/23863947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.hd.124aa0d16753f88215776fba102ceb29
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