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Inhibition of Ron kinase blocks conversion of micrometastases to overt metastases by boosting anti-tumor immunity

Many “non-metastatic” cancers have spawned undetectable metastases prior to diagnosis. Eventual outgrowth of these microscopic lesions causes metastatic relapse and death, yet the events that dictate when and how micrometastases convert to overt metastases are largely unknown. We report that macroph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eyob, Henok, Ekiz, Huseyin Atakan, DeRose, Yoko S., Waltz, Susan E., Williams, Matthew A., Welm, Alana L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710539/
https://ncbi.nlm.nih.gov/pubmed/23612011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0480
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