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RON promotes the metastatic spread of breast carcinomas by subverting antitumor immune responses
The MSP/RON signaling pathway favors the conversion of micrometastatic lesions to overt metastases by suppressing antitumor immune responses. The loss of RON functions in the host potentiates tumor-specific CD8(+) T-cell responses, hence inhibiting the outgrowth of metastatic cancer cells. Thus, RON...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3850023/ https://ncbi.nlm.nih.gov/pubmed/24327933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25670 |
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