Inhibition of RON kinase potentiates anti-CTLA-4 immunotherapy to shrink breast tumors and prevent metastatic outgrowth

The advent of immune checkpoint blockade as a new strategy for immunotherapy has changed the outlook for many aggressive cancers. Although complete tumor eradication is attainable in some cases, durable clinical responses are observed only in a small fraction of patients, underlining urgent need for...

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Опубликовано в: :Oncoimmunology
Главные авторы: Ekiz, Huseyin Atakan, Lai, Shu-Chin Alicia, Gundlapalli, Harika, Haroun, Fadi, Williams, Matthew A., Welm, Alana L.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2018
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140584/
https://ncbi.nlm.nih.gov/pubmed/30228950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1480286
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