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Diacylglycerol kinase alpha is a critical signaling node and novel therapeutic target in glioblastoma and other cancers
While Diacylglycerol kinase alpha (DGKα) has been linked to several signaling pathways related to cancer cell biology, it has been neglected as a target for cancer therapy. The attenuation of DGKα activity via DGKα-targeting siRNA and small-molecule inhibitors, R59022 and R59949, induced caspase-med...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710531/ https://ncbi.nlm.nih.gov/pubmed/23558954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0215 |
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