A carregar...
Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch
The Notch pathway is dysregulated and a potential target in glioblastoma multiforme (GBM). Currently available Notch inhibitors block γ-secretase, which is necessary for Notch processing. However, Notch is first cleaved by α-secretase outside the plasma membrane, via a disintegrin and metalloprotein...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3452340/ https://ncbi.nlm.nih.gov/pubmed/22962413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos157 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|