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The Poliovirus Replication Machinery Can Escape Inhibition by an Antiviral Drug That Targets a Host Cell Protein

Viral replication depends on specific interactions with host factors. For example, poliovirus RNA replication requires association with intracellular membranes. Brefeldin A (BFA), which induces a major rearrangement of the cellular secretory apparatus, is a potent inhibitor of poliovirus RNA replica...

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Detalhes bibliográficos
Main Authors: Crotty, Shane, Saleh, Maria-Carla, Gitlin, Leonid, Beske, Oren, Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371039/
https://ncbi.nlm.nih.gov/pubmed/15016860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3378-3386.2004
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