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Manganese-Dependent Polioviruses Caused by Mutations within the Viral Polymerase

Viral RNA-dependent RNA polymerases exhibit great sequence diversity. Only six core amino acids are conserved across all polymerases of positive-strand RNA viruses of eukaryotes. While exploring the function of one of these completely conserved residues, asparagine 297 in the prototypic poliovirus p...

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Detalhes bibliográficos
Main Authors: Crotty, Shane, Gohara, David, Gilligan, Devin K., Karelsky, Sveta, Cameron, Craig E., Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153957/
https://ncbi.nlm.nih.gov/pubmed/12692240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5378-5388.2003
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