Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA Polymerase

Poliovirus 3CD is a multifunctional protein that serves as a precursor to the protease 3C(pro) and the viral polymerase 3D(pol) and also plays a role in the control of viral replication. Although 3CD is a fully functional protease, it lacks polymerase activity. We have solved the crystal structures...

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Detalhes bibliográficos
Main Authors: Marcotte, Laura L., Wass, Amanda B., Gohara, David W., Pathak, Harsh B., Arnold, Jamie J., Filman, David J., Cameron, Craig E., Hogle, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866080/
https://ncbi.nlm.nih.gov/pubmed/17251299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02306-06
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