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Single-Cell Analysis Uncovers Extensive Biological Noise in Poliovirus Replication

Viral infections often begin with a very small number of initiating particles. Accordingly, the outcome of an infection is likely to be affected by variability in the initial molecular interactions between virus and host. In this study, we investigated the range of outcomes upon infection of single...

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Bibliografiske detaljer
Main Authors: Schulte, Michael B., Andino, Raul
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093869/
https://ncbi.nlm.nih.gov/pubmed/24648454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03539-13
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