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Single-Cell Analysis Uncovers Extensive Biological Noise in Poliovirus Replication

Viral infections often begin with a very small number of initiating particles. Accordingly, the outcome of an infection is likely to be affected by variability in the initial molecular interactions between virus and host. In this study, we investigated the range of outcomes upon infection of single...

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Detalhes bibliográficos
Main Authors: Schulte, Michael B., Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093869/
https://ncbi.nlm.nih.gov/pubmed/24648454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03539-13
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