Vaccinia virus protein K7 is a virulence factor that alters the acute immune response to infection

Vaccinia virus (VACV) encodes many proteins that antagonize the innate immune system including a family of intracellular proteins with a B-cell lymphoma (Bcl)-2-like structure. One of these Bcl-2 proteins called K7 binds Toll-like receptor-adaptor proteins and the DEAD-box RNA helicase DDX3 and ther...

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Main Authors: Benfield, Camilla T. O., Ren, Hongwei, Lucas, Stuart J., Bahsoun, Basma, Smith, Geoffrey L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for General Microbiology 2013
Ábhair:
Animal
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709632/
https://ncbi.nlm.nih.gov/pubmed/23580427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.052670-0
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