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Leaky scanning translation generates a second A49 protein that contributes to vaccinia virus virulence
Vaccinia virus (VACV) strain Western Reserve gene A49L encodes a small intracellular protein with a Bcl-2 fold that is expressed early during infection and has multiple functions. A49 co-precipitates with the E3 ubiquitin ligase β-TrCP and thereby prevents ubiquitylation and proteasomal degradation...
Guardat en:
| Publicat a: | J Gen Virol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Microbiology Society
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7414448/ https://ncbi.nlm.nih.gov/pubmed/32100702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001386 |
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