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Evaluating quantitative methods for measuring plasmid copy numbers in single cells

The life of plasmids is a constant battle against fluctuations: failing to correct copy number fluctuations can increase the plasmid loss rate by many orders of magnitude, as can a failure to more evenly divide the copies between daughters at cell division. Plasmids are therefore long-standing model...

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Detalhes bibliográficos
Main Authors: Tal, Shay, Paulsson, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709585/
https://ncbi.nlm.nih.gov/pubmed/22305922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plasmid.2012.01.004
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