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High-Copy-Number Plasmid Segregation—Single-Molecule Dynamics in Single Cells
Bacterial high-copy-number (hcn) plasmids provide an excellent model to study the underlying physical mechanisms of DNA segment segregation in an intracellular context. Using two-color fluorescent repressor-operator systems and a synthetic repressible replication origin, we tracked the motion and se...
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| Publié dans: | Biophys J |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400962/ https://ncbi.nlm.nih.gov/pubmed/30773297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.019 |
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