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β-selection-induced proliferation is required for αβ T cell differentiation
Proliferation and differentiation are tightly coordinated to produce an appropriate number of differentiated cells, and often exhibit an antagonistic relationship. Developing T cells, that arise in the thymus from a minute number of bone marrow-derived progenitors, undergo a major expansion upon pre...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3709258/ https://ncbi.nlm.nih.gov/pubmed/23159226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.08.020 |
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