Salicylate-aspirin interaction in the rat. Evidence that salicylate accumulating during aspirin administration may protect vascular prostacyclin from aspirin-induced inhibition.

Aspirin inhibits cyclooxygenase, thus preventing thromboxane A2 production in blood platelets and prostacyclin in vascular cells. Aspirin is rapidly hydrolyzed to salicylate in the circulation. The objectives of this study were (a) to evaluate whether administration of salicylate, though ineffective...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Dejana, E, Cerletti, C, de Castellarnau, C, Livio, M, Galletti, F, Latini, R, de Gaetano, G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1981
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC370901/
https://ncbi.nlm.nih.gov/pubmed/6793630
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk