Genetic Variation in COMT: Effects on Working Memory in Schizophrenic Patients, Their Siblings, & Healthy Controls

BACKGROUND: COMT val(108/158)met (rs4680) is thought to affect dopamine regulated prefrontal cortical activity during working memory (WM) tasks, and to weakly increase risk for developing schizophrenia. Recently, other single nucleotide polymorphisms (SNPs) across the gene have emerged as additional...

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Detaylı Bibliyografya
Asıl Yazarlar: Diaz-Asper, Catherine M., Goldberg, Terry E., Kolachana, Bhaskar S., Straub, Richard E., Egan, Michael F., Weinberger, Daniel R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708610/
https://ncbi.nlm.nih.gov/pubmed/17707347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.03.031
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