Brain-Derived Neurotrophic Factor val(66)met Polymorphism Affects Human Memory-Related Hippocampal Activity and Predicts Memory Performance

BDNF plays a critical role in activity-dependent neuroplasticity underlying learning and memory in the hippocampus. A frequent single nucleotide polymorphism in the targeting region of the human BDNF gene (val(66)met) has been associated with abnormal intracellular trafficking and regulated secretio...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Hariri, Ahmad R., Goldberg, Terry E., Mattay, Venkata S., Kolachana, Bhaskar S., Callicott, Joseph H., Egan, Michael F., Weinberger, Daniel R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Brief Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740735/
https://ncbi.nlm.nih.gov/pubmed/12890761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-17-06690.2003
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