Impact of the Brain Derived Neurotrophic Factor Val66Met Polymorphism on Levels of Hippocampal N-Acetyl Aspartate Assessed by Magnetic Resonance Spectroscopic Imaging at 3 Tesla

BACKGROUND: This study was conducted to corroborate prior evidence of an effect of the BDNF Val66Met polymorphism on measures of N-acetyl aspartate containing compounds (NAA) in healthy subjects. METHODS: The NAA to creatine (Cre) ratio (NAA/Cre), NAA to choline (Cho) ratio (NAA/Cho), and Cho to Cre...

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Main Authors: Stern, Alexa J., Savostyanova, Antonina A., Goldman, Aaron, Barnett, Alan S., van der Veen, Jan Willem C., Callicott, Joseph H., Mattay, Venkata S., Weinberger, Daniel R., Marenco, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586327/
https://ncbi.nlm.nih.gov/pubmed/18707679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.07.009
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