Brain-Derived Neurotrophic Factor (BDNF) Val(66)Met Polymorphism Differentially Predicts Hippocampal Function in Medication-Free Patients with Schizophrenia

A Val(66)Met single nucleotide polymorphism (SNP) in the brain-derived neurotrophic factor (BDNF) gene impairs activity-dependent BDNF release in cultured hippocampal neurons and predicts impaired memory and exaggerated basal hippocampal activity in healthy humans. Several clinical genetic associati...

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Detalhes bibliográficos
Main Authors: Eisenberg, Daniel Paul, Ianni, Angela M., Wei, Shau-Ming, Kohn, Philip D., Kolachana, Bhaskar, Apud, José, Weinberger, Daniel R., Berman, Karen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628926/
https://ncbi.nlm.nih.gov/pubmed/23319002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.187
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