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Brain-Derived Neurotrophic Factor (BDNF) Val(66)Met Polymorphism Differentially Predicts Hippocampal Function in Medication-Free Patients with Schizophrenia
A Val(66)Met single nucleotide polymorphism (SNP) in the brain-derived neurotrophic factor (BDNF) gene impairs activity-dependent BDNF release in cultured hippocampal neurons and predicts impaired memory and exaggerated basal hippocampal activity in healthy humans. Several clinical genetic associati...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628926/ https://ncbi.nlm.nih.gov/pubmed/23319002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.187 |
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