Genetic Variation in COMT: Effects on Working Memory in Schizophrenic Patients, Their Siblings, & Healthy Controls

BACKGROUND: COMT val(108/158)met (rs4680) is thought to affect dopamine regulated prefrontal cortical activity during working memory (WM) tasks, and to weakly increase risk for developing schizophrenia. Recently, other single nucleotide polymorphisms (SNPs) across the gene have emerged as additional...

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Bibliografische gegevens
Hoofdauteurs: Diaz-Asper, Catherine M., Goldberg, Terry E., Kolachana, Bhaskar S., Straub, Richard E., Egan, Michael F., Weinberger, Daniel R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708610/
https://ncbi.nlm.nih.gov/pubmed/17707347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.03.031
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