Genetic Variation in COMT: Effects on Working Memory in Schizophrenic Patients, Their Siblings, & Healthy Controls

BACKGROUND: COMT val(108/158)met (rs4680) is thought to affect dopamine regulated prefrontal cortical activity during working memory (WM) tasks, and to weakly increase risk for developing schizophrenia. Recently, other single nucleotide polymorphisms (SNPs) across the gene have emerged as additional...

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Detalhes bibliográficos
Main Authors: Diaz-Asper, Catherine M., Goldberg, Terry E., Kolachana, Bhaskar S., Straub, Richard E., Egan, Michael F., Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708610/
https://ncbi.nlm.nih.gov/pubmed/17707347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.03.031
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