The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells

The nuclear cap-binding complex (CBC) binds to the 7-methyl guanosine cap present on every RNA polymerase II transcript. CBC has been implicated in many aspects of RNA biogenesis; in addition to roles in miRNA biogenesis, nonsense-mediated decay, 3′-end formation, and snRNA export from the nucleus,...

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Bibliografiske detaljer
Main Authors: Pabis, Marta, Neufeld, Noa, Steiner, Michaela C., Bojic, Teodora, Shav-Tal, Yaron, Neugebauer, Karla M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2013
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708526/
https://ncbi.nlm.nih.gov/pubmed/23793891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037069.112
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