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SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome.

Pre-spliceosomes, formed in HeLa nuclear extracts and isolated by sedimentation on glycerol gradients, were chased into spliceosomes, the macromolecular enzyme that catalyzes intron removal. We demonstrate that the pre-spliceosome to spliceosome transition was dependent on ATP hydrolysis and require...

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Bibliografiska uppgifter
Huvudupphovsmän: Roscigno, R F, Garcia-Blanco, M A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369311/
https://ncbi.nlm.nih.gov/pubmed/7585254
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