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A central role of plasmin in cardiac injury initiated by fetal exposure to maternal anti-Ro autoantibodies
Objective. Cardiac neonatal lupus (cardiac-NL), initiated by surface binding of anti-Ro60 autoantibodies to apoptotic cardiocytes during development, activates the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system. Subsequent accumulation of apoptotic cells a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708522/ https://ncbi.nlm.nih.gov/pubmed/23598443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ket156 |
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