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Modulation of natural IgM autoantibodies to oxidative stress-related neo-epitopes on apoptotic cells in newborns of mothers with anti-Ro autoimmunity

At birth, the human immune system already contains substantial levels of polymeric IgM, with autoantibodies to neo-epitopes on apoptotic cells (ACs) that are proposed to play homeostatic and anti-inflammatory roles. Yet the biologic origins and developmental regulation of these naturally arising ant...

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Dettagli Bibliografici
Pubblicato in:J Autoimmun
Autori principali: Grönwall, Caroline, Clancy, Robert M., Getu, Lelise, Lloyd, Katy A., Siegel, Don L., Reed, Joanne H., Buyon, Jill, Silverman, Gregg J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003717/
https://ncbi.nlm.nih.gov/pubmed/27289167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.05.014
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