A central role of plasmin in cardiac injury initiated by fetal exposure to maternal anti-Ro autoantibodies

Objective. Cardiac neonatal lupus (cardiac-NL), initiated by surface binding of anti-Ro60 autoantibodies to apoptotic cardiocytes during development, activates the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system. Subsequent accumulation of apoptotic cells a...

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Autors principals: Briassouli, Paraskevi, Halushka, Marc K., Reed, Joanne H., Molad, Yair, Fox-Talbot, Karen, Buyon, Lucas, Guzman, Edwin, Ludomirsky, Achiau, Clancy, Robert M., Buyon, Jill P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Clinical Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708522/
https://ncbi.nlm.nih.gov/pubmed/23598443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ket156
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