Simultaneous and Sensitive Detection of Human Immunodeficiency Virus Type 1 (HIV) Drug Resistant Genotypes by Multiplex Oligonucleotide Ligation Assay

Oligonucleotide ligation assay (OLA) is a highly specific and relatively simple method to detect point mutations encoding HIV-1 drug-resistance, which can detect mutants comprising ≥2–5% of the viral population. Nevirapine (NVP), tenofovir (TDF) and lamivudine (3TC) are antiretroviral drugs (ARV) us...

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Hauptverfasser: Ellis, Giovanina M., Marushchak, Tatyana A., Koth, Andrew, Vaz, Louise E., Dross, Sandra E., Beck, Ingrid A., Frenkel, Lisa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708483/
https://ncbi.nlm.nih.gov/pubmed/23660583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2011.11.030
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