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Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives
The secondary bile acid lithocholic acid (LCA) and its derivatives act as selective modulators of the vitamin D receptor (VDR), although their structures fundamentally differ from that of the natural hormone 1α,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3))]. Here, we have determined the crystal structu...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The American Society for Biochemistry and Molecular Biology
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708370/ https://ncbi.nlm.nih.gov/pubmed/23723390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M038307 |
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