A2B Adenosine Receptor Blockade Enhances Macrophage-Mediated Bacterial Phagocytosis and Improves Polymicrobial Sepsis Survival in Mice

Antimicrobial treatment strategies must improve to reduce the high mortality rates in septic patients. In noninfectious models of acute inflammation, activation of A2B adenosine receptors (A2BR) in extracellular adenosine-rich microenvironments causes immunosuppression. We examined A2BR in antibacte...

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Detaylı Bibliyografya
Asıl Yazarlar: Belikoff, Bryan G., Hatfield, Stephen, Georgiev, Peter, Ohta, Akio, Lukashev, Dmitriy, Buras, Jon A., Remick, Daniel G., Sitkovsky, Michail
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708265/
https://ncbi.nlm.nih.gov/pubmed/21242513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001567
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