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ADENOSINE NEGATIVE FEEDBACK ON A2A ADENOSINE RECEPTORS MEDIATES HYPORESPONSIVENESS IN CHRONICALLY SEPTIC MICE
Strategies are needed to reverse the immune cell hyporesponsiveness and prevent bacterial overgrowth associated with high mortality rates in septic patients. Adenosine signaling may be mediating immunosuppressive signals within the inflammatory microenvironment that are safeguarding bacteria by rend...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693562/ https://ncbi.nlm.nih.gov/pubmed/21192284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3182085f12 |
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