Overexpression of GATA1 Confers Resistance to Chemotherapy in Acute Megakaryocytic Leukemia

It has been previously shown that acute myeloid leukemia (AML) patients with higher levels of GATA1 expression have poorer outcomes. Furthermore, pediatric Down syndrome (DS) patients with acute megakaryocytic leukemia (AMKL), whose blast cells almost universally harbor somatic mutations in exon 2 o...

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Autores principales: Caldwell, John Timothy, Edwards, Holly, Dombkowski, Alan A., Buck, Steven A., Matherly, Larry H., Ge, Yubin, Taub, Jeffrey W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707876/
https://ncbi.nlm.nih.gov/pubmed/23874683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068601
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