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Unraveling the complexities of SIRT1-mediated mitochondrial regulation in skeletal muscle

SIRT1 is a purported central regulator of skeletal muscle mitochondrial biogenesis. Herein we discuss our recent work utilizing conditional mouse models, which highlight the complexities of SIRT1 biology in vivo, and question its role in regulating mitochondrial function and mitochondrial adaptions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Philp, Andrew, Schenk, Simon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707796/
https://ncbi.nlm.nih.gov/pubmed/23792490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JES.0b013e3182956803
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