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Unraveling the complexities of SIRT1-mediated mitochondrial regulation in skeletal muscle
SIRT1 is a purported central regulator of skeletal muscle mitochondrial biogenesis. Herein we discuss our recent work utilizing conditional mouse models, which highlight the complexities of SIRT1 biology in vivo, and question its role in regulating mitochondrial function and mitochondrial adaptions...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707796/ https://ncbi.nlm.nih.gov/pubmed/23792490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JES.0b013e3182956803 |
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