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Protein Kinase A-Iα Regulates Na,K-ATPase Endocytosis in Alveolar Epithelial Cells Exposed to High CO(2) Concentrations
Elevated concentrations of CO(2) (hypercapnia) lead to alveolar epithelial dysfunction by promoting Na,K-ATPase endocytosis. In the present report, we investigated whether the CO(2)/HCO(3)(−) activated soluble adenylyl cyclase (sAC) regulates this process. We found that hypercapnia increased the pro...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Thoracic Society
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707378/ https://ncbi.nlm.nih.gov/pubmed/23349050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0373OC |
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