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The Long-Range P3 Helix of the Tetrahymena Ribozyme Is Disrupted During Folding Between the Native and Misfolded Conformations
RNAs are prone to misfolding, but how misfolded structures are formed and resolved remains incompletely understood. The Tetrahymena group I intron ribozyme folds in vitro to a long-lived misfolded conformation (M) that includes extensive native structure but is proposed to differ in topology from th...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706569/ https://ncbi.nlm.nih.gov/pubmed/23702292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.05.008 |
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