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Inhibition of Apurinic/apyrimidinic endonuclease I’s redox activity revisited
The essential base excision repair protein, apurinic/apyrimidinic endonuclease 1 (APE1), plays an important role in redox regulation in cells and is currently targeted for development of cancer therapeutics. One compound that binds APE1 directly is (E)-3-(2-(5,6-dimethoxy-3-methyl-1,4-benzoquinonyl)...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706204/ https://ncbi.nlm.nih.gov/pubmed/23597102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400179m |
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