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Inhibition of Apurinic/apyrimidinic endonuclease I’s redox activity revisited

The essential base excision repair protein, apurinic/apyrimidinic endonuclease 1 (APE1), plays an important role in redox regulation in cells and is currently targeted for development of cancer therapeutics. One compound that binds APE1 directly is (E)-3-(2-(5,6-dimethoxy-3-methyl-1,4-benzoquinonyl)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Jun, Luo, Meihua, Marasco, Daniela, Logsdon, Derek, LaFavers, Kaice A., Chen, Qiujia, Reed, April, Kelley, Mark R., Gross, Michael L., Georgiadis, Millie M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706204/
https://ncbi.nlm.nih.gov/pubmed/23597102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400179m
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