Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii

DNA repair is essential for cell viability and proliferation. In addition to reactive oxygen produced as a byproduct of their own metabolism, intracellular parasites also have to manage oxidative stress generated as a defense mechanism by the host. The spontaneous loss of DNA bases due to hydrolysis...

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Bibliographic Details
Main Authors: Onyango, David O., Naguleswaran, Arunasalam, Delaplane, Sarah, Reed, April, Kelley, Mark R., Georgiadis, Millie M., Sullivan, William J.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084321/
https://ncbi.nlm.nih.gov/pubmed/21353648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.01.011
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