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Ubiquitin-Like Domain of IKKβ Regulates Osteoclastogenesis and Osteolysis
The transcription factor NF-κB family is central for osteoclastogenesis and inflammatory osteolysis. Activation of NF-κB dimers is regulated by a kinase complex predominantly containing IKKα (IKK1), IKKβ (IKK2), and a regulatory subunit, IKKγ/NEMO. IKKα and IKKβ catalyze the cytoplasmic liberation a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706195/ https://ncbi.nlm.nih.gov/pubmed/23686246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-013-9735-5 |
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