Specific α4β2 Nicotinic Acetylcholine Receptor Binding of [F-18]Nifene in the Rhesus Monkey

OBJECTIVE: [F-18]Nifene is a PET radioligand developed to image α4β2* nicotinic acetylcholine receptors (nAChR) in the brain. This work assesses the in vivo binding and imaging characteristics of [F-18]nifene in rhesus monkeys for the development of PET experiments examining nAChR binding. METHODS:...

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Main Authors: Hillmer, A.T., Wooten, D.W., Moirano, J., Slesarev, M., Barnhart, T.E., Engle, J.W., Nickles, R.J., Murali, D., Schneider, M., Mukherjee, J., Christian, B.T.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705633/
https://ncbi.nlm.nih.gov/pubmed/21674627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20965
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