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Disease-relevant proteostasis regulation of cystic fibrosis transmembrane conductance regulator
Mismanaged protein trafficking by the proteostasis network contributes to several conformational diseases, including cystic fibrosis, the most frequent lethal inherited disease in Caucasians. Proteostasis regulators, as cystamine, enable the beneficial action of cystic fibrosis transmembrane conduct...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705602/ https://ncbi.nlm.nih.gov/pubmed/23686137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.46 |
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