Simvastatin Increases Phosphorylation of Akt and its Downstream Signaling Targets and Suppresses Apoptosis after Traumatic Brain Injury

OBJECT: Our previous studies found that simvastatin treatment of traumatic brain injury (TBI) in rats had beneficial effects on spatial learning functions. In the current study we wanted to determine whether simvastatin suppressed neuronal cell apoptosis after TBI, and if so, the underlying mechanis...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Hongtao, Lu, Dunyue, Jiang, Hao, Xiong, sYe, Qu, Changsheng, Li, Bo, Mahmood, Asim, Zhou, Dong, Chopp, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703644/
https://ncbi.nlm.nih.gov/pubmed/18826357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/JNS/2008/109/10/0691
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