Induction of angiogenesis and modulation of VEGFR-2 by simvastatin after traumatic brain injury

BACKGROUND: Our previous studies demonstrated that simvastatin reduced neuronal death, increased neurogenesis, and promoted functional recovery after TBI. Objective: To investigate the effect of simvastatin on angiogenesis after TBI, and the related signaling pathways. METHODS: Saline or simvastatin...

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Hlavní autoři: Wu, Hongtao, Jiang, Hao, Lu, Dunyue, Qu, Changsheng, Xiong, Ye, Zhou, Dong, Chopp, Michael, Mahmood, Asim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119744/
https://ncbi.nlm.nih.gov/pubmed/21307798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0b013e31820c06b9
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